I've beaten on this poor horse before, but I don't think it's dead yet. So I'm going to whack away some more.
I just got a comment from someone with MGUS (Monoclonal Gammopathy of Undetermined Significance) who responded to my previous June 10 post about Lyme Disease: More on Lyme. This person suffered from Lyme Disease in 2011, which went untreated for months, until the symptoms became significant. She (I think it is a she, but I'm not sure, since the post response was anonymous) finally got on some serious antibiotics, which brought the symptoms under control. But then in 2012, she was diagnosed with IgA MGUS.
This is a familiar story. It's my story, complete with the IgA diagnosis. She wonders if there is any connection between Lyme and MGUS/MM, particularly the IgA type. Hello! In her comment, she makes a rather serious accusation, and I quote, "one of the oncolog i saw said they know amongst themselves that lyme can trigger mgus but since lyme is so politicized and polarized they all keep their mouths shut while people suffer." Wow! I really hope this is not the case, but based on my past experience with the medical community on Lyme, it wouldn't surprise me at all.
As you know from reading my past blog posts, I have been fixated on the possible connection between Lyme Disease and myeloma for a long time. The commenter asked a pertinent question that I have been asking myself for a while: "I have wondered whether the assault on my immune triggered the IGA MGUS that I have or whether I had the iga mgus first and the lyme made it express itself when attacked." I have a gut feeling that contracting Lyme Disease suppresses the immune system to the point that any latent monoclonal gammopathy might be unleashed. My blog commenter theorizes that it might specifically trigger IgA-type gammopathy. I don't know. Maybe so.
I have a favor to ask of those reading my blog. If any of you have contracted MGUS, SMM or MM, I would appreciate it is you could respond either to my blog or directly to me by email (email@example.com) whether you have ever previously had Lyme Disease or suffered from undiagnosed Lyme Disease type symptoms prior to your diagnosis. Please include your type of gammopathy (IgG, IgA, etc.). This is an informal survey, as I'm trying to determine if there is any discernible pattern that would connect Lyme to MGUS, SMM, or MM. Any anecdotal stories would be of interest. I would like to compile some information that might possibly shed some light on this issue.
Thank you in advance for your cooperation. I promise to keep any information you send me strictly confidential. What happens in Vegas stays in Vegas!