|Claudia, Paul, and me|
I think the side effects of these drugs are starting to get to me a little bit. The dexamethasone is messing up my sleep patterns so it's hard to tell day from night. I didn't feel great yesterday, so I spent most of the day resting. I also found out from Richardson on Wednesday that my diarrhea may also be from the Revlimid, technically denoted as "Revy Belly". It's nice to have a name for it. I got a prescription for Colestipol to take next week to help keep it from recurring.
Now that my dental issues have been resolved, I finally got my first IV infusion of the bisphosphonate Zometa on Wednesday. This should help protect my bones against the ravages of MM. I have been very fortunate so far to have escaped any serious bone involvement. I think I am supposed to take Zometa on a monthly basis going forward.
I finally made the decision to go ahead with the ASCT, so I signed the consent forms for the transplant clinical trial. After this current Cycle 7, things get pretty hectic. I go through some pretesting later this month, and then on March 2, I start the stem cell collection process. According to the current schedule, I will go into Brigham and Women's Hospital on March 17 (Happy St. Patrick's Day!) for the stem cell infusion. I will probably spend about 18 days in the hospital if all goes well. There is a possibility that I may delay the transplant another month or so and go back on the MLN9708 for another cycle or two if I am still responding to the treatment, but the most likely scenario is for me to go directly to the ASCT. I'd better enjoy life for the next month, because I won't enjoy it much for a while after that.